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Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics
Yu, N. Z.; S. L. Wang; Y. S. Liu; P. H. Xue; P. Ge; J. J. Nan; S. S. Ye; W. D. Liu; J. H. Zhang and B. Yang
2017
Source PublicationLangmuir
Volume33Issue:2
AbstractWe show morphology-patterned stripes modified by thermal-responsive polymer for smartly guiding, flow motion of fluid in chips. With a two-step modification process, we fabricated PNIPAAm-modified Si stripes on silicon: slides, which were employed as substrates for fluid manipulation in microchannels. When the system temperature switches between above and below the lower critical solution temperature (LCST) of PNIPAAm, the wettability of the substrates also switches between strong anisotropy and weak anisotropy, which resulted in anisotropic (even unidirectional) flow and isotropic flow behavior of liquid in microchannels. The thermal-responsive flow motion of fluid in the chip is influenced by the applied pressure, the thickness of PNIPAAm, and dimension of the microchannels. Moreover, we measured the feasible applied pressure scopes under different structure factors. Because of the excellent reversibility and quick switching speed, the chip could be used as a thermal-responsive microvalve. Through tuning the system temperature and adding the assistant gas, we realized successive "valve" function. We believe that the practical and simple chip could be widely utilized in medical detection, immunodetection, protein analysis, and cell cultures.
Indexed Bysci ; ei
Language英语
Document Type期刊论文
Identifierhttp://ir.ciomp.ac.cn/handle/181722/59401
Collection中科院长春光机所知识产出
Recommended Citation
GB/T 7714
Yu, N. Z.,S. L. Wang,Y. S. Liu,et al. Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics[J]. Langmuir,2017,33(2).
APA Yu, N. Z..,S. L. Wang.,Y. S. Liu.,P. H. Xue.,P. Ge.,...&J. H. Zhang and B. Yang.(2017).Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics.Langmuir,33(2).
MLA Yu, N. Z.,et al."Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics".Langmuir 33.2(2017).
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