Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics

	Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics
	Yu, N. Z.; S. L. Wang; Y. S. Liu; P. H. Xue; P. Ge; J. J. Nan; S. S. Ye; W. D. Liu; J. H. Zhang and B. Yang
	2017
发表期刊	Langmuir
卷号	33 期号:2
摘要	We show morphology-patterned stripes modified by thermal-responsive polymer for smartly guiding, flow motion of fluid in chips. With a two-step modification process, we fabricated PNIPAAm-modified Si stripes on silicon: slides, which were employed as substrates for fluid manipulation in microchannels. When the system temperature switches between above and below the lower critical solution temperature (LCST) of PNIPAAm, the wettability of the substrates also switches between strong anisotropy and weak anisotropy, which resulted in anisotropic (even unidirectional) flow and isotropic flow behavior of liquid in microchannels. The thermal-responsive flow motion of fluid in the chip is influenced by the applied pressure, the thickness of PNIPAAm, and dimension of the microchannels. Moreover, we measured the feasible applied pressure scopes under different structure factors. Because of the excellent reversibility and quick switching speed, the chip could be used as a thermal-responsive microvalve. Through tuning the system temperature and adding the assistant gas, we realized successive "valve" function. We believe that the practical and simple chip could be widely utilized in medical detection, immunodetection, protein analysis, and cell cultures.
收录类别	sci ; ei
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/59401
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Yu, N. Z.,S. L. Wang,Y. S. Liu,et al. Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics[J]. Langmuir,2017,33(2).
APA	Yu, N. Z..,S. L. Wang.,Y. S. Liu.,P. H. Xue.,P. Ge.,...&J. H. Zhang and B. Yang.(2017).Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics.Langmuir,33(2).
MLA	Yu, N. Z.,et al."Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics".Langmuir 33.2(2017).

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