A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood

	A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood
	Li, X. K.; Y. L. Zhang; B. Xue; X. G. Kong; X. M. Liu; L. P. Tu; Y. L. Chang and H. Zhang
	2017
发表期刊	Biosensors & Bioelectronics
卷号	92
摘要	Assay technologies capable of detecting biomarker concentrations in unprocessed whole blood samples are fundamental for applications in medical diagnostics. SERS nano-tags integrated fiber-optic biosensor (FOB) was realized for the first time for in situ immunoassay in whole blood. The reliability and sensitivity of this method rely, in a large extent, on the quality and properties of the SERS nano-tags. The constructed silica coated Ag SERS nano-tags as labels were used in a rapid and specific in situ FOB immune sensor to detect alpha fetoprotein (AFP) in unprocessed blood samples. Preliminary results of in vivo and in situ dynamic observation of AFP of whole blood in wistar rat highlight the power of this new method.
收录类别	sci ; ei
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/59024
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Li, X. K.,Y. L. Zhang,B. Xue,et al. A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood[J]. Biosensors & Bioelectronics,2017,92.
APA	Li, X. K..,Y. L. Zhang.,B. Xue.,X. G. Kong.,X. M. Liu.,...&Y. L. Chang and H. Zhang.(2017).A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood.Biosensors & Bioelectronics,92.
MLA	Li, X. K.,et al."A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood".Biosensors & Bioelectronics 92(2017).

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