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A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood
Li, X. K.; Y. L. Zhang; B. Xue; X. G. Kong; X. M. Liu; L. P. Tu; Y. L. Chang and H. Zhang
2017
发表期刊Biosensors & Bioelectronics
卷号92
摘要Assay technologies capable of detecting biomarker concentrations in unprocessed whole blood samples are fundamental for applications in medical diagnostics. SERS nano-tags integrated fiber-optic biosensor (FOB) was realized for the first time for in situ immunoassay in whole blood. The reliability and sensitivity of this method rely, in a large extent, on the quality and properties of the SERS nano-tags. The constructed silica coated Ag SERS nano-tags as labels were used in a rapid and specific in situ FOB immune sensor to detect alpha fetoprotein (AFP) in unprocessed blood samples. Preliminary results of in vivo and in situ dynamic observation of AFP of whole blood in wistar rat highlight the power of this new method.
收录类别sci ; ei
语种英语
文献类型期刊论文
条目标识符http://ir.ciomp.ac.cn/handle/181722/59024
专题中科院长春光机所知识产出
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GB/T 7714
Li, X. K.,Y. L. Zhang,B. Xue,et al. A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood[J]. Biosensors & Bioelectronics,2017,92.
APA Li, X. K..,Y. L. Zhang.,B. Xue.,X. G. Kong.,X. M. Liu.,...&Y. L. Chang and H. Zhang.(2017).A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood.Biosensors & Bioelectronics,92.
MLA Li, X. K.,et al."A SERS nano-tag-based fiber-optic strategy for in situ immunoassay in unprocessed whole blood".Biosensors & Bioelectronics 92(2017).
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