Disparity between online and offline tests in accelerated aging tests of LED lamps under electric stress

	Disparity between online and offline tests in accelerated aging tests of LED lamps under electric stress
	Wang, Y.; L. Jing; H. L. Ke; J. Hao; Q. Gao; X. X. Wang; Q. Sun and Z. J. Xu
	2016
发表期刊	Applied Optics
卷号	55 期号:27
摘要	The dysfunction of subthalamic nucleus is the main cause of Parkinson's disease. Local field potentials in human subthalamic nucleus contain rich physiological information. The present study aimed to quantify the oscillatory and dynamic characteristics of local field potentials of subthalamic nucleus, and their modulation by the medication therapy for Parkinson's disease. The subthalamic nucleus local field potentials were recorded from patients with Parkinson's disease at the states of on and off medication. The oscillatory features were characterised with the power spectral analysis. Furthermore, the dynamic features were characterised with time-frequency analysis and the coefficient of variation measure of the time-variant power at each frequency. There was a dominant peak at low beta band with medication off. The medication significantly suppressed the low beta component and increased the theta component. The amplitude fluctuation of neural oscillations was measured by the coefficient of variation. The coefficient of variation in 4-7 Hz and 60-66 Hz was increased by medication. These effects proved that medication had significant modulation to subthalamic nucleus neural oscillatory synchronization and dynamic features. The subthalamic nucleus neural activities tend towards stable state under medication. The findings would provide quantitative biomarkers for studying the mechanisms of Parkinson's disease and clinical treatments of medication or deep brain stimulation. 2016, Editorial Office of Journal of Biomedical Engineering. All right reserved.
文章类型	期刊
收录类别	SCI ; EI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/57257
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Wang, Y.,L. Jing,H. L. Ke,et al. Disparity between online and offline tests in accelerated aging tests of LED lamps under electric stress[J]. Applied Optics,2016,55(27).
APA	Wang, Y..,L. Jing.,H. L. Ke.,J. Hao.,Q. Gao.,...&Q. Sun and Z. J. Xu.(2016).Disparity between online and offline tests in accelerated aging tests of LED lamps under electric stress.Applied Optics,55(27).
MLA	Wang, Y.,et al."Disparity between online and offline tests in accelerated aging tests of LED lamps under electric stress".Applied Optics 55.27(2016).

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Disparity between on（745KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载