Changchun Institute of Optics,Fine Mechanics and Physics,CAS
Cerebral alterations of type 2 diabetes mellitus on MRI: A pilot study | |
Peng, B.; Z. Y. Chen; L. Ma and Y. K. Dai | |
2015 | |
发表期刊 | Neuroscience Letters |
卷号 | 606页码:100-105 |
摘要 | This study is to investigate gray matter volume, cortical thickness, and surface area of the brain in patients with type 2 diabetes mellitus (T2DM). High resolution T1-weighted MR images were obtained from eighteen T2DM and seventeen normal controls. All images were processed using our newly developed BrainLab toolbox. Declines of gray matter volume, cortical thickness, and surface area were found in T2DM patients. Significantly reduced ROIs of gray matter volume happened in subcortical gray nuclei (left caudate and right caudate), and significantly reduced ROIs of cortical thickness occurred in temporal lobe (left superior temporal gyrus), parietal lobe (left angular gyrus), and occipital lobe (right superior occipital gyrus, left middle occipital gyrus and right cuneus). Apparently reduced ROIs of surface area were mainly distributed in frontal lobe (right superior frontal gyrus (dorsal) and left paracentral lobule). The findings indicated that T2DM caused brain changes in specific regions. This work revealed neural alterations of T2DM, which had a great significance in early diagnosis of the disease. (C) 2015 Elsevier Ireland Ltd. All rights reserved. |
收录类别 | SCI |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ciomp.ac.cn/handle/181722/55374 |
专题 | 中科院长春光机所知识产出 |
推荐引用方式 GB/T 7714 | Peng, B.,Z. Y. Chen,L. Ma and Y. K. Dai. Cerebral alterations of type 2 diabetes mellitus on MRI: A pilot study[J]. Neuroscience Letters,2015,606:100-105. |
APA | Peng, B.,Z. Y. Chen,&L. Ma and Y. K. Dai.(2015).Cerebral alterations of type 2 diabetes mellitus on MRI: A pilot study.Neuroscience Letters,606,100-105. |
MLA | Peng, B.,et al."Cerebral alterations of type 2 diabetes mellitus on MRI: A pilot study".Neuroscience Letters 606(2015):100-105. |
条目包含的文件 | 下载所有文件 | |||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Peng-2015-Cerebral a(1829KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论