Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips

	Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips
	Deng Y. B.; Fan J. H.; Zhou S.; Zhou T.; Wu J. F.; Li Y.; Liu Z. Y.; Xuan M.; Wu Y. H.
	2014
发表期刊	Biomicrofluidics
ISSN	ISBN/1932-1058
卷号	8 期号:2 页码:18
摘要	Based on the Euler force induced by the acceleration of compact disk (CD)-like microfluidic chip, this paper presents a novel actuation mechanism for siphon valving. At the preliminary stage of acceleration, the Euler force in the tangential direction of CD-like chip takes the primary place compared with the centrifugal force to function as the actuation of the flow, which fills the siphon and actuates the siphon valving. The Euler force actuation mechanism is demonstrated by the numerical solution of the phase-field based mathematical model for the flow in siphon valve. In addition, experimental validation is implemented in the polymethylmethacrylate-based CD-like microfluidic chip manufactured using CO2 laser engraving technique. To prove the application of the proposed Euler force actuation mechanism, whole blood separation and plasma extraction has been conducted using the Euler force actuated siphon valving. The newly introduced actuation mechanism overcomes the dependence on hydrophilic capillary filling of siphon by avoiding external manipulation or surface treatments of polymeric material. The sacrifice for highly integrated processing in pneumatic pumping technique is also prevented by excluding the volume-occupied compressed air chamber. (C) 2014 AIP Publishing LLC.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/43976
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Deng Y. B.,Fan J. H.,Zhou S.,et al. Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips[J]. Biomicrofluidics,2014,8(2):18.
APA	Deng Y. B..,Fan J. H..,Zhou S..,Zhou T..,Wu J. F..,...&Wu Y. H..(2014).Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips.Biomicrofluidics,8(2),18.
MLA	Deng Y. B.,et al."Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips".Biomicrofluidics 8.2(2014):18.

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