Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody

	Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody
其他题名	论文其他题名
	Wang L. Y.; Ji X. H.; Yuan H.; Ma L.; Kong X. G.; Liu Y. C.; Yang W. S.; Bai Y. B.; Li T. J.
	2002
发表期刊	Acta Chimica Sinica
ISSN	0567-7351
卷号	60 期号:12 页码:2115-2119
摘要	Surface-enhanced Raman scattering (SERS) has been employed to study the interaction of hepatitis B virus surface antigen (HBsAg) with mouse monoclonal antibody against HBsAg (Ab-HBsAg). SERS is used to obtain spectra of HBsAg, Ab-HBsAg and their immune complex adsorbed on colloidal silver. It is found that Ab-HBsAg is bound to silver colloids through the carboxyl groups, which are not on the antigen binding site of the Ab-HBsAg. The vibrations from tryptophan residues of the HBsAg disappear after formation of the immune complex. It is assumed that the tryptophan residues are among the antigen active sites of the HBsAg and play an important role in the interaction between Ab-HBsAg and HBsAg.
收录类别	SCI
语种	中文
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/25855
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Wang L. Y.,Ji X. H.,Yuan H.,et al. Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody[J]. Acta Chimica Sinica,2002,60(12):2115-2119.
APA	Wang L. Y..,Ji X. H..,Yuan H..,Ma L..,Kong X. G..,...&Li T. J..(2002).Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody.Acta Chimica Sinica,60(12),2115-2119.
MLA	Wang L. Y.,et al."Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody".Acta Chimica Sinica 60.12(2002):2115-2119.

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