Ratiometric nanothermometer CaSc2O4: Nd3+ operating in biological window for deep-tissue photothermal therapy

doi:10.1016/j.ceramint.2022.12.260

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	Ratiometric nanothermometer CaSc2O4: Nd3+ operating in biological window for deep-tissue photothermal therapy
	G. T. Xiang, M. L. Yang, Y. X. Ding, H. X. Wu, L. Yao, Y. J. Wang, X. J. Zhou, L. Li, L. Ma, X. J. Wang and J. H. Zhang
	2023
发表期刊	Ceramics International
ISSN	0272-8842
卷号	49 期号:9 页码:13816-13822
摘要	Accurate and real-time temperature detection is an urgent requirement in photothermal therapy (PTT). In this work, the CaSc2O4: Nd3+ nanorod with an average length of 150 nm has been determined to be an outstanding optical thermometer based on the fluorescence intensity ratio (FIR) of thermally coupled Stark sublevels of Nd3+: 4F3/2 -> 4I11/2 transition, of which the excitation and emission wavelength are located in the first and second biological window respectively, resulting in an 8 mm penetration depth in the biological tissues. The maximal absolute sensitivity and relative sensitivity as well as the minimal temperature resolution of the present sample is 0.0008 K-1, 0.0018 K-1 and 0.19 K respectively, which is superior to the vast majority of the same type ther-mometers. Besides that, the nanorods show a 7 K temperature increment after 180 s' 808 nm-laser radiation, revealing its photothermal conversion capacity thanks to the considerable nonradiative relaxation processes among the metastable energy levels of Nd3+. These results indicate that Nd3+ single-doped CaSc2O4 nanorods can be utilized as the optical thermometer in the deep-tissue PTT process for real-time thermometry along with the function of light-to-heat conversion.
DOI	10.1016/j.ceramint.2022.12.260
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收录类别	sci ; ei
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/68549
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	G. T. Xiang, M. L. Yang, Y. X. Ding, H. X. Wu, L. Yao, Y. J. Wang, X. J. Zhou, L. Li, L. Ma, X. J. Wang and J. H. Zhang. Ratiometric nanothermometer CaSc2O4: Nd3+ operating in biological window for deep-tissue photothermal therapy[J]. Ceramics International,2023,49(9):13816-13822.
APA	G. T. Xiang, M. L. Yang, Y. X. Ding, H. X. Wu, L. Yao, Y. J. Wang, X. J. Zhou, L. Li, L. Ma, X. J. Wang and J. H. Zhang.(2023).Ratiometric nanothermometer CaSc2O4: Nd3+ operating in biological window for deep-tissue photothermal therapy.Ceramics International,49(9),13816-13822.
MLA	G. T. Xiang, M. L. Yang, Y. X. Ding, H. X. Wu, L. Yao, Y. J. Wang, X. J. Zhou, L. Li, L. Ma, X. J. Wang and J. H. Zhang."Ratiometric nanothermometer CaSc2O4: Nd3+ operating in biological window for deep-tissue photothermal therapy".Ceramics International 49.9(2023):13816-13822.

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