Customized High-Sensitivity Plasmonic Metasensing Towards Immunodetection of Single Bio-Nanoparticles

doi:10.1109/JSTQE.2023.3235723

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	Customized High-Sensitivity Plasmonic Metasensing Towards Immunodetection of Single Bio-Nanoparticles
	J. Shen, F. Li, Z. Wang, X. Liu, Y. Xie, W. Chen, M. H. Fang and J. Zhu
	2023
发表期刊	IEEE Journal of Selected Topics in Quantum Electronics
ISSN	1077260X
卷号	29 期号:4
摘要	Plasmonic metasurface biosensing has shown great potential in label-free detection of bio-nanoparticles with various sizes, such as cancer antigens, exosomes and SARS-CoV-2 virus. It typically relies on the immunoassay, but current studies usually neglect the perfect size matching between each target bio-nanoparticle and the surface near-field domain, which should be very critical for the enhancement of detection performance. In order to maximize the immunodetection capability for each bio-nanoparticle, we propose a plasmonic meta-biosensor based on the field-customized mechanism. Our design overcomes the serious interference of biofunctionalization and accomplishes a sensitivity of 27 times higher than the conventional nanoplasmonic counterpart. Our method also builds the important basis of single bio-nanoparticle immunodetection by a plasmonic metasurface. The customized plasmonic metasensing study implies a promising way towards ultra-low concentration biosensing or even single bio-nanoparticle detection for high-performance point-of-care-testing in the near future. © 1995-2012 IEEE.
DOI	10.1109/JSTQE.2023.3235723
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收录类别	sci ; ei
引用统计
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/67836
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	J. Shen, F. Li, Z. Wang, X. Liu, Y. Xie, W. Chen, M. H. Fang and J. Zhu. Customized High-Sensitivity Plasmonic Metasensing Towards Immunodetection of Single Bio-Nanoparticles[J]. IEEE Journal of Selected Topics in Quantum Electronics,2023,29(4).
APA	J. Shen, F. Li, Z. Wang, X. Liu, Y. Xie, W. Chen, M. H. Fang and J. Zhu.(2023).Customized High-Sensitivity Plasmonic Metasensing Towards Immunodetection of Single Bio-Nanoparticles.IEEE Journal of Selected Topics in Quantum Electronics,29(4).
MLA	J. Shen, F. Li, Z. Wang, X. Liu, Y. Xie, W. Chen, M. H. Fang and J. Zhu."Customized High-Sensitivity Plasmonic Metasensing Towards Immunodetection of Single Bio-Nanoparticles".IEEE Journal of Selected Topics in Quantum Electronics 29.4(2023).

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