Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies

doi:10.3390/antiox12040920

CIOMP OpenIR

	Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies
	J. H. Qiao, C. X. Wang, Y. Chen, S. Yu, Y. Liu, S. T. Yu, L. L. Jiang, C. R. Jin, X. R. Wang, P. G. Zhang, D. Q. Zhao, J. W. Wang and M. C. Liu
	2023
发表期刊	Antioxidants
卷号	12 期号:4 页码:20
摘要	Aging is a complex process of impaired physiological integrity and function, and is associated with increased risk of cardiovascular disease, diabetes, neurodegeneration, and cancer. The cellular environment of the aging brain exhibits perturbed bioenergetics, impaired adaptive neuroplasticity and flexibility, abnormal neuronal network activity, dysregulated neuronal Ca2+ homeostasis, accumulation of oxidatively modified molecules and organelles, and clear signs of inflammation. These changes make the aging brain susceptible to age-related diseases, such as Alzheimer's and Parkinson's diseases. In recent years, unprecedented advances have been made in the study of aging, especially the effects of herbal/natural compounds on evolutionarily conserved genetic pathways and biological processes. Here, we provide a comprehensive review of the aging process and age-related diseases, and we discuss the molecular mechanisms underlying the therapeutic properties of herbal/natural compounds against the hallmarks of brain aging.
DOI	10.3390/antiox12040920
URL	查看原文
收录类别	sci
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/67798
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	J. H. Qiao, C. X. Wang, Y. Chen, S. Yu, Y. Liu, S. T. Yu, L. L. Jiang, C. R. Jin, X. R. Wang, P. G. Zhang, D. Q. Zhao, J. W. Wang and M. C. Liu. Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies[J]. Antioxidants,2023,12(4):20.
APA	J. H. Qiao, C. X. Wang, Y. Chen, S. Yu, Y. Liu, S. T. Yu, L. L. Jiang, C. R. Jin, X. R. Wang, P. G. Zhang, D. Q. Zhao, J. W. Wang and M. C. Liu.(2023).Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies.Antioxidants,12(4),20.
MLA	J. H. Qiao, C. X. Wang, Y. Chen, S. Yu, Y. Liu, S. T. Yu, L. L. Jiang, C. R. Jin, X. R. Wang, P. G. Zhang, D. Q. Zhao, J. W. Wang and M. C. Liu."Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies".Antioxidants 12.4(2023):20.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Herbal_Natural Compo（3665KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览下载