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Research progress of miniature head-mounted single photon fluorescence microscopic imaging technique
Q. Fu; Z.-M. Zhang; S.-N. Zhao; Y. Liu and Y. Dong
2023
发表期刊Chinese Optics
ISSN20971842
卷号16期号:5页码:1010-1021
摘要Miniature head-mounted single-photon fluorescence microscopy is a breakthrough approach for neuroscience research that has emerged in recent years. It can image the neural activity of freely moving vivo animals in real time, providing an unprecedented way to access neural signals and rapidly enhancing the understanding of how the brain works. Driven by the needs of brain science research, there have been many types of miniature head-mounted single-photon fluorescence microscopes, such as high-resolution imaging, wireless recording, 3D imaging, two-region imaging and two-color imaging. In order to have a more comprehensive understanding of this new optical neuroimaging technology, we classify its technologies according to the imaging field of view, introduce the characteristics of different types of micro-head-mounted single-photon fluorescence microscopes reported so far, and focus on the optical system scheme and optical performance parameters used. The advantages and disadvantages of different schemes are analyzed and compared and the future direction of development is described to provide reference for the practical application of brain science researchers. © 2023 Editorial Office of Chinese Optics. All rights reserved.
DOI10.37188/CO.2023-0007
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条目标识符http://ir.ciomp.ac.cn/handle/181722/67465
专题中国科学院长春光学精密机械与物理研究所
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Q. Fu,Z.-M. Zhang,S.-N. Zhao,et al. Research progress of miniature head-mounted single photon fluorescence microscopic imaging technique[J]. Chinese Optics,2023,16(5):1010-1021.
APA Q. Fu,Z.-M. Zhang,S.-N. Zhao,&Y. Liu and Y. Dong.(2023).Research progress of miniature head-mounted single photon fluorescence microscopic imaging technique.Chinese Optics,16(5),1010-1021.
MLA Q. Fu,et al."Research progress of miniature head-mounted single photon fluorescence microscopic imaging technique".Chinese Optics 16.5(2023):1010-1021.
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