User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)

doi:10.1021/acs.analchem.0c03827

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	User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)
	K. Wang; L. He; A. Manz and W. Wu
	2021
发表期刊	Analytical Chemistry
ISSN	32700
卷号	93 期号:3 页码:1523-1528
摘要	One of the most important challenges in the field of microfluidics is the rapid fabrication of microchips with complex topologies. Although the processing method of microfluidic chips has made brilliant achievements in the past 20 years, almost all traditional processing methods still face huge obstacles in the production of complex topologies and three-dimensional microchannel. Nowadays, the main methods of manufacturing microfluidic chips such as numerical control microprocessing, laser ablation, inkjet printing, photolithography, dry etching, and lithography, galvanoformung and abformung (LIGA) technology are not only inapplicable to the complex topological structure and the rapid processing of three-dimensional microfluidic chips but also rely on expensive processing equipment, complex manufacturing process, and low yield. To solve the problems of these traditional processing methods, we propose a low-cost methodology to obtain a microfluidic chip by sewing the chip pipe to the substrate with an embroidery machine as low as $6. Compared with the above-mentioned traditional microprocessing technologies, the new chip processing technology proposed by us does not involve professional microprocessing equipment and professional skills. Therefore, this new chip processing technology can significantly improve the efficiency of microprocessing. 2020 American Chemical Society
DOI	10.1021/acs.analchem.0c03827
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收录类别	SCI ; EI
引用统计
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/65738
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	K. Wang,L. He,A. Manz and W. Wu. User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)[J]. Analytical Chemistry,2021,93(3):1523-1528.
APA	K. Wang,L. He,&A. Manz and W. Wu.(2021).User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR).Analytical Chemistry,93(3),1523-1528.
MLA	K. Wang,et al."User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)".Analytical Chemistry 93.3(2021):1523-1528.

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