Changchun Institute of Optics,Fine Mechanics and Physics,CAS
Mesoporous silica-coated upconverting nanorods for singlet oxygen generation: Synthesis and performance | |
Z. Zhang; X.-L. Zhang and B. Li | |
2021 | |
发表期刊 | Materials |
ISSN | 19961944 |
卷号 | 14期号:13 |
摘要 | Photodynamic therapy (PDT) has been reported as a possible pathway for the treatment of tumors. The exploration for promising PDT systems thus attracts continuous research efforts. This work focused on an ordered coreshell structure encapsulated by mesoporous SiO2 with the upconverting emission property following a surfactant-assisted solgel technique. The mesoporous silica shell possessed a high surface area-to-volume ratio and uniform distribution in pore size, favoring photosensitizer (rose bengal) loading. Simultaneously, upconverting nanocrystals were synthesized and used as the core. After modification via hydrophobic silica, the hydrophobic upconverting nanocrystals became hydrophilic ones. Under near-infrared (NIR) light irradiation, the nanomaterials exhibited strong green upconverting luminescence so that rose bengal could be excited to produce singlet oxygen. The photodynamic therapy (PDT) feature was evaluated using a1O2 fluorescent indicator. It was found that this coreshell structure generates1O2 efficiently. The novelty of this coreshell structure was the combination of upconverting nanocrystals with a mesoporous SiO2 shell so that photosensitizer rose bengal could be effectively adsorbed in the SiO2 shell and then excited by the upconverting core. 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
DOI | 10.3390/ma14133660 |
URL | 查看原文 |
收录类别 | SCI ; EI |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ciomp.ac.cn/handle/181722/65409 |
专题 | 中国科学院长春光学精密机械与物理研究所 |
推荐引用方式 GB/T 7714 | Z. Zhang,X.-L. Zhang and B. Li. Mesoporous silica-coated upconverting nanorods for singlet oxygen generation: Synthesis and performance[J]. Materials,2021,14(13). |
APA | Z. Zhang,&X.-L. Zhang and B. Li.(2021).Mesoporous silica-coated upconverting nanorods for singlet oxygen generation: Synthesis and performance.Materials,14(13). |
MLA | Z. Zhang,et al."Mesoporous silica-coated upconverting nanorods for singlet oxygen generation: Synthesis and performance".Materials 14.13(2021). |
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