Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy

doi:10.1002/adma.201904836

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	Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy
	Q.S.Wang; H.Wang; Y.Yang; L.H.Jin; Y.Liu; Y.Wang; X.Y.Yan
	2019
发表期刊	Advanced Materials
ISSN	0935-9648
卷号	31 期号:46 页码:7
摘要	Photothermal therapy triggered by near-infrared light in the second biowindow (NIR-II) has attracted extensive interest owing to its deeper penetration depth of biological tissue, lower photon scattering, and higher maximum permissible exposure. In spite of noble metals showing great potential as the photothermal agents due to the tunable localized surface plasmon resonance, the biological applications of platinum are rarely explored. Herein, a monocomponent hollow Pt nanoframe ("Pt Spirals"), whose superstructure is assembled with three levels (3D frame, 2D layered shells, and 1D nanowires), is reported. Pt Spirals exhibit outstanding photothermal conversion efficiency (52.5%) and molar extinction coefficients (228.7 m(2) mol(-1)) in NIR-II, which are much higher than those of solid Pt cubes. Simulations indicate that the unique superstructure can be a significant cause for improving both adsorption and the photothermal effect simultaneously in NIR-II. The excellent photothermal effect is achieved and subsequently verified in in vitro and in vivo experiments, along with superb heat-resistance properties, excellent photostability, and a prominent effect on computed tomography (CT) imaging, demonstrating that Pt Spirals are promising as effective theranostic platforms for CT imaging-guided photothermal therapy.
关键词	NIR-II biowindow,photothermal therapy,plasmons,platinum,superstructures,optical-absorption,nanoparticles,platinum,gold,nanocrystals,relaxation,nanodots,nanorods,nanostructures,dynamics,Chemistry,Science & Technology - Other Topics,Materials Science,Physics
DOI	10.1002/adma.201904836
收录类别	SCI ; EI
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/62997
专题	中国科学院长春光学精密机械与物理研究所
推荐引用方式 GB/T 7714	Q.S.Wang,H.Wang,Y.Yang,et al. Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy[J]. Advanced Materials,2019,31(46):7.
APA	Q.S.Wang.,H.Wang.,Y.Yang.,L.H.Jin.,Y.Liu.,...&X.Y.Yan.(2019).Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy.Advanced Materials,31(46),7.
MLA	Q.S.Wang,et al."Plasmonic Pt Superstructures with Boosted Near-Infrared Absorption and Photothermal Conversion Efficiency in the Second Biowindow for Cancer Therapy".Advanced Materials 31.46(2019):7.

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