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Carbon nanodots and their composites for biomedical applications
Wang Xiao-yun, 王晓筠; Li Bo, 李 波; Chen Li, 陈 力; Li Di, 李 迪; Qu Song-nan, 曲松楠; Li Zhi-min, 李志民
2018
发表期刊Chinese Optics
ISSN2095-1531
卷号11期号:3页码:401-419
摘要As an emerging carbon nanomaterial, carbon nanodots(CNDs) have many advantages such as low preparation cost, small size, low toxicity, high biocompatibility, good water solubility, easy modification, unique photophysical properties, and exhibit unique advantages and application prospects in the field of biomedicine. Taking advantage of the abundant surface functional groups, carbon nanodots can interact with functional theranostic agents such as targeting ligands, contrast agents in medical imaging, nucleic acids, chemical drugs, photosensitizers, and photothermal conversion reagents to form composites. Currently, bioluminescent imaging applications of carbon nanodots and their composites in biomedical theranostic fields such as medical imaging, gene therapy, chemotherapy, photothermal therapy, and photodynamic therapy are widely studied and reported. These researches are of great significance to the development of medical theranostic reagents based on carbon nanodots and their clinical advancement, and provide a novel drug system for the advancement of individualized, visualized, non-invasive, and minimally invasive diagnosis and treatment of major human diseases. This paper focuses on the design, construction and performance of carbon nanodots and their composites used in the field of theranostics. In addition, the research progress of the reported carbon nanodots based theranostic reagents in the biomedical field is discussed and summarized. 2018, China Science Publishing & Media LTD. All right reserved.
关键词Nanodots Biocompatibility Chemotherapy Clinical research Diagnosis Gene therapy Medical applications Medical imaging Medical nanotechnology Nanostructured materials Nucleic acids Photodynamic therapy Photosensitizers
DOI10.3788/co.20181103.0401
收录类别EI
引用统计
文献类型期刊论文
条目标识符http://ir.ciomp.ac.cn/handle/181722/60590
专题中国科学院长春光学精密机械与物理研究所
推荐引用方式
GB/T 7714
Wang Xiao-yun, 王晓筠,Li Bo, 李 波,Chen Li, 陈 力,et al. Carbon nanodots and their composites for biomedical applications[J]. Chinese Optics,2018,11(3):401-419.
APA Wang Xiao-yun, 王晓筠,Li Bo, 李 波,Chen Li, 陈 力,Li Di, 李 迪,Qu Song-nan, 曲松楠,&Li Zhi-min, 李志民.(2018).Carbon nanodots and their composites for biomedical applications.Chinese Optics,11(3),401-419.
MLA Wang Xiao-yun, 王晓筠,et al."Carbon nanodots and their composites for biomedical applications".Chinese Optics 11.3(2018):401-419.
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