Europium-decorated ZnO quantum dots as a fluorescent sensor for the detection of an anthrax biomarker

	Europium-decorated ZnO quantum dots as a fluorescent sensor for the detection of an anthrax biomarker
	Zhou, R.; Q. Zhao; K. K. Liu; Y. J. Lu; L. Dong and C. X. Shan
	2017
发表期刊	Journal of Materials Chemistry C
卷号	5 期号:7
摘要	A hybrid nanostructure based on ZnO quantum dots (QDs) has been fabricated for ratiometric detection of Bacillus anthracis spores, where yellow-emitting ZnO QDs are employed as the internal reference and europium ions (Eu3+) are chelated on the surface of the ZnO QDs as the signal report unit. The Eu3+ exhibits enhanced red luminescence upon bonding with calcium dipicolinate (CaDPA), an important biomarker of Bacillus anthracis spores, while the fluorescence of the ZnO QDs will not be altered. Accordingly, increased CaDPA levels can lead to variation of the two fluorescence intensity ratios of the ZnO/Eu hybrid nanostructure. The time-dependent fluorescence response reveals that the reaction can be completed within 8 s, thus enabling the rapid detection of Bacillus anthracis spores. The detection limit for CaDPA is 3 nM, which is six orders of magnitude lower than an infectious dosage of Bacillus anthracis spores for human beings (60 mM). In addition, the sensor shows a remarkable selectivity for CaDPA over other aromatic ligands, amino acids and common cellular ions. The fast response speed as well as good sensitivity and selectivity means the ZnO/Eu nanostructure has great potential applications in clinical analysis.
收录类别	sci ; ei
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/59497
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Zhou, R.,Q. Zhao,K. K. Liu,et al. Europium-decorated ZnO quantum dots as a fluorescent sensor for the detection of an anthrax biomarker[J]. Journal of Materials Chemistry C,2017,5(7).
APA	Zhou, R.,Q. Zhao,K. K. Liu,Y. J. Lu,&L. Dong and C. X. Shan.(2017).Europium-decorated ZnO quantum dots as a fluorescent sensor for the detection of an anthrax biomarker.Journal of Materials Chemistry C,5(7).
MLA	Zhou, R.,et al."Europium-decorated ZnO quantum dots as a fluorescent sensor for the detection of an anthrax biomarker".Journal of Materials Chemistry C 5.7(2017).

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Europium decorated Z（2651KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载