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Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics
Yu, N. Z.; S. L. Wang; Y. S. Liu; P. H. Xue; P. Ge; J. J. Nan; S. S. Ye; W. D. Liu; J. H. Zhang and B. Yang
2017
发表期刊Langmuir
卷号33期号:2
摘要We show morphology-patterned stripes modified by thermal-responsive polymer for smartly guiding, flow motion of fluid in chips. With a two-step modification process, we fabricated PNIPAAm-modified Si stripes on silicon: slides, which were employed as substrates for fluid manipulation in microchannels. When the system temperature switches between above and below the lower critical solution temperature (LCST) of PNIPAAm, the wettability of the substrates also switches between strong anisotropy and weak anisotropy, which resulted in anisotropic (even unidirectional) flow and isotropic flow behavior of liquid in microchannels. The thermal-responsive flow motion of fluid in the chip is influenced by the applied pressure, the thickness of PNIPAAm, and dimension of the microchannels. Moreover, we measured the feasible applied pressure scopes under different structure factors. Because of the excellent reversibility and quick switching speed, the chip could be used as a thermal-responsive microvalve. Through tuning the system temperature and adding the assistant gas, we realized successive "valve" function. We believe that the practical and simple chip could be widely utilized in medical detection, immunodetection, protein analysis, and cell cultures.
收录类别sci ; ei
语种英语
文献类型期刊论文
条目标识符http://ir.ciomp.ac.cn/handle/181722/59401
专题中科院长春光机所知识产出
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Yu, N. Z.,S. L. Wang,Y. S. Liu,et al. Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics[J]. Langmuir,2017,33(2).
APA Yu, N. Z..,S. L. Wang.,Y. S. Liu.,P. H. Xue.,P. Ge.,...&J. H. Zhang and B. Yang.(2017).Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics.Langmuir,33(2).
MLA Yu, N. Z.,et al."Thermal-Responsive Anisotropic Wetting Microstructures for Manipulation of Fluids in Microfluidics".Langmuir 33.2(2017).
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