Development of an implantable optrode for optogenetic stimulation

	Development of an implantable optrode for optogenetic stimulation
	Yue, S.; M. Yuan; Y. Zhang; X. Wang and S. Wang
	2016
发表期刊	Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering
卷号	33 期号:2
摘要	The misalignment between recorded in-focus and out-of-focus images using the Phase Diversity (PD) algorithm leads to a dramatic decline in wavefront detection accuracy and image recovery quality for segmented active optics systems. This paper demonstrates the theoretical relationship between the image misalignment and tip-tilt terms in Zernike polynomials of the wavefront phase for the first time, and an efficient two-step alignment correction algorithm is proposed to eliminate these misalignment effects. This algorithm processes a spatial 2-D cross-correlation of the misaligned images, revising the offset to 1 or 2 pixels and narrowing the search range for alignment. Then, it eliminates the need for subpixel fine alignment to achieve adaptive correction by adding additional tip-tilt terms to the Optical Transfer Function (OTF) of the out-of-focus channel. The experimental results demonstrate the feasibility and validity of the proposed correction algorithm to improve the measurement accuracy during the co-phasing of segmented mirrors. With this alignment correction, the reconstructed wavefront is more accurate, and the recovered image is of higher quality.
文章类型	期刊
收录类别	EI
语种	中文
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/57393
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Yue, S.,M. Yuan,Y. Zhang,et al. Development of an implantable optrode for optogenetic stimulation[J]. Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering,2016,33(2).
APA	Yue, S.,M. Yuan,Y. Zhang,&X. Wang and S. Wang.(2016).Development of an implantable optrode for optogenetic stimulation.Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering,33(2).
MLA	Yue, S.,et al."Development of an implantable optrode for optogenetic stimulation".Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering 33.2(2016).

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