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Highly sensitive optical nanofiber sensor based on gold nanorod amplification
Li, M.; K. Li; F. Dai; W. Zhou; F. Shu and Y. Wu
2015
发表期刊Guangxue Xuebao/Acta Optica Sinica
卷号35期号:12
摘要In order to meet the requirements of high sensitivity and specificity of biomedical research, a new optical nanofiber biosensor using gold nanorods (GNR) as amplification labels is reported, based on extinction property of GNR. Optical influence of GNR attached to the surface of fiber is studied. Single GNR is successfully resolved in experiment. In this nanofiber biosensor, a sandwich assay strategy is utilized for detection. The limit of detection (LOD) of this sensor for Goat-IgG is 0.02 ng/mL in PBS, which shows a great performance in sensitivity and specificity. The biosensor, reported in this work, has the advantages of simple detection scheme, fast response time, and ease of miniaturization, which might make this biosensor a promising platform for clinical cancer diagnosis, food safety detection and environmental monitoring. 2015, Chinese Laser Prees. All right reserved.
文章类型期刊论文
收录类别EI
文献类型期刊论文
条目标识符http://ir.ciomp.ac.cn/handle/181722/56170
专题中科院长春光机所知识产出
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GB/T 7714
Li, M.,K. Li,F. Dai,et al. Highly sensitive optical nanofiber sensor based on gold nanorod amplification[J]. Guangxue Xuebao/Acta Optica Sinica,2015,35(12).
APA Li, M.,K. Li,F. Dai,W. Zhou,&F. Shu and Y. Wu.(2015).Highly sensitive optical nanofiber sensor based on gold nanorod amplification.Guangxue Xuebao/Acta Optica Sinica,35(12).
MLA Li, M.,et al."Highly sensitive optical nanofiber sensor based on gold nanorod amplification".Guangxue Xuebao/Acta Optica Sinica 35.12(2015).
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