Retinal axial focusing and multi-layer imaging with a liquid crystal adaptive optics camera

	Retinal axial focusing and multi-layer imaging with a liquid crystal adaptive optics camera
	Liu R. X.; Zheng X. L.; Li D. Y.; Xia M. L.; Hu L. F.; Cao Z. L.; Mu Q. Q.; Xuan L.
	2014
发表期刊	中文 Physics B
ISSN	ISBN/1674-1056
卷号	23 期号:9 页码:9
摘要	With the help of adaptive optics (AO) technology, cellular level imaging of living human retina can be achieved. Aiming to reduce distressing feelings and to avoid potential drug induced diseases, we attempted to image retina with dilated pupil and froze accommodation without drugs. An optimized liquid crystal adaptive optics camera was adopted for retinal imaging. A novel eye stared system was used for stimulating accommodation and fixating imaging area. Illumination sources and imaging camera kept linkage for focusing and imaging different layers. Four subjects with diverse degree of myopia were imaged. Based on the optical properties of the human eye, the eye stared system reduced the defocus to less than the typical ocular depth of focus. In this way, the illumination light can be projected on certain retina layer precisely. Since that the defocus had been compensated by the eye stared system, the adopted 512 x 512 liquid crystal spatial light modulator (LC-SLM) corrector provided the crucial spatial fidelity to fully compensate high-order aberrations. The Strehl ratio of a subject with - diopter myopia was improved to 0.78, which was nearly close to diffraction-limited imaging. By finely adjusting the axial displacement of illumination sources and imaging camera, cone photoreceptors, blood vessels and nerve fiber layer were clearly imaged successfully.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/44351
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Liu R. X.,Zheng X. L.,Li D. Y.,et al. Retinal axial focusing and multi-layer imaging with a liquid crystal adaptive optics camera[J]. 中文 Physics B,2014,23(9):9.
APA	Liu R. X..,Zheng X. L..,Li D. Y..,Xia M. L..,Hu L. F..,...&Xuan L..(2014).Retinal axial focusing and multi-layer imaging with a liquid crystal adaptive optics camera.中文 Physics B,23(9),9.
MLA	Liu R. X.,et al."Retinal axial focusing and multi-layer imaging with a liquid crystal adaptive optics camera".中文 Physics B 23.9(2014):9.

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