Patient specific respiratory motion modeling using a limited number of 3D lung CT images

	Patient specific respiratory motion modeling using a limited number of 3D lung CT images
	Cui X. L.; Gao X.; Xia W.; Liu Y. C.; Liang Z. Y.
	2014
发表期刊	Bio-Medical Materials and Engineering
ISSN	ISBN/0959-2989
卷号	24 期号:6 页码:3113-3120
摘要	To build a patient specific respiratory motion model with a low dose, a novel method was proposed that uses a limited number of 3D lung CT volumes with an external respiratory signal. 4D lung CT volumes were acquired for patients with in vitro labeling on the upper abdominal surface. Meanwhile, 3D coordinates of in vitro labeling were measured as external respiratory signals. A sequential correspondence between the 4D lung CT and the external respiratory signal was built using the distance correlation method, and a 3D displacement for every registration control point in the CT volumes with respect to time can be obtained by the 4D lung CT deformable registration. A temporal fitting was performed for every registration control point displacements and an external respiratory signal in the anterior-posterior direction respectively to draw their fitting curves. Finally, a linear regression was used to fit the corresponding samples of the control point displacement fitting curves and the external respiratory signal fitting curve to finish the pulmonary respiration modeling. Compared to a B-spline-based method using the respiratory signal phase, the proposed method is highly advantageous as it offers comparable modeling accuracy and target modeling error (TME); while at the same time, the proposed method requires 70% less 3D lung CTs. When using a similar amount of 3D lung CT data, the mean of the proposed method's TME is smaller than the mean of the PCA (principle component analysis)-based methods' TMEs. The results indicate that the proposed method is successful in striking a balance between modeling accuracy and number of 3D lung CT volumes.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/44256
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Cui X. L.,Gao X.,Xia W.,et al. Patient specific respiratory motion modeling using a limited number of 3D lung CT images[J]. Bio-Medical Materials and Engineering,2014,24(6):3113-3120.
APA	Cui X. L.,Gao X.,Xia W.,Liu Y. C.,&Liang Z. Y..(2014).Patient specific respiratory motion modeling using a limited number of 3D lung CT images.Bio-Medical Materials and Engineering,24(6),3113-3120.
MLA	Cui X. L.,et al."Patient specific respiratory motion modeling using a limited number of 3D lung CT images".Bio-Medical Materials and Engineering 24.6(2014):3113-3120.

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