Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods

	Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods
	Li H.; Tan L. L.; Jia P.; Li Q. L.; Sun Y. L.; Zhang J.; Ning Y. Q.; Yu J. H.; Yang Y. W.
	2014
发表期刊	Chemical Science
ISSN	ISBN/2041-6520
卷号	5 期号:7 页码:2804-2808
摘要	We constructed a novel cancer theranostic hybrid platform, based on mesoporous silica-coated gold nanorods (AuNR@MSN) gated by sulfonatocalix[4] arene (SC[4] A) switches, for bio-friendly near-infrared (NIR) light-triggered cargo release in a remote and stepwise fashion. The advantages of supramolecular switches, mesoporous silicas, and AuNRs were combined in one drug delivery system. Mesoporous silicas coated on AuNRs guarantee a high drug payload and can be easily post-functionalized. Significantly, the plasmonic heating from the NIR light-stimulated AuNR cores can decrease the ringstalk binding affinity, leading to the dissociation of SC[4] A rings from the stalks, thus opening the nanovalves and releasing the cargos. The NIR light-responsive mechanized AuNR@MSN offers exciting prospects for non-invasive controlled drug delivery, being more effective and safer than other techniques.
收录类别	SCI ; EI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/44185
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Li H.,Tan L. L.,Jia P.,et al. Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods[J]. Chemical Science,2014,5(7):2804-2808.
APA	Li H..,Tan L. L..,Jia P..,Li Q. L..,Sun Y. L..,...&Yang Y. W..(2014).Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods.Chemical Science,5(7),2804-2808.
MLA	Li H.,et al."Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods".Chemical Science 5.7(2014):2804-2808.

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