Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs

	Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs
	He H.; Zhou L.; Wang Y.; Li C.; Yao J.; Zhang W.; Zhang Q.; Li M.; Li H.; Dong W.-F.
	2014
发表期刊	Talanta
ISSN	ISBN/00399140
期号	131 页码:8-13
摘要	A 20 MHz quartz crystal microbalance (QCM) sensor coated with in situ self-assembled molecularly imprinted polymers (MIPs) was presented for the detection of trace microcystin-LR (MC-LR) in drinking water. The sensor performance obtained using the in situ self-assembled MIPs was compared with traditionally synthesized MIPs on 20 MHz and normal 10 MHz QCM chip. The results show that the response increases by more than 60% when using the in situ self-assembly method compared using the traditionally method while the 20 MHz QCM chip provides four-fold higher response than the 10 MHz one. Therefore, the in situ self-assembled MIPs coated on a high frequency QCM chip was used in the sensor performance test to detect MC-LR in tap water. It showed a limit of detection (LOD) of 0.04 nM which is lower than the safety guideline level (1 nM MC-LR) of drinking water in China. The low sensor response to other analogs indicated the high specificity of the sensor to MC-LR. The sensor showed high stability and low signal variation less than 2.58% after regeneration. The lake water sample analysis shows the sensor is possible for practical use. The combination of the higher frequency QCM with the in situ self-assembled MIPs provides a good candidate for the detection of other small molecules. 2014 Elsevier B.V. All rights reserved.
收录类别	EI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/43886
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	He H.,Zhou L.,Wang Y.,et al. Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs[J]. Talanta,2014(131):8-13.
APA	He H..,Zhou L..,Wang Y..,Li C..,Yao J..,...&Dong W.-F..(2014).Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs.Talanta(131),8-13.
MLA	He H.,et al."Detection of trace microcystin-LR on a 20 MHz QCM sensor coated with in situ self-assembled MIPs".Talanta .131(2014):8-13.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
He-2014-Detection of（1243KB）			开放获取	CC BY-ND	浏览请求全文