Changchun Institute of Optics,Fine Mechanics and Physics,CAS
Experimental Study of Differential Spectrum Method for Elimination of Tissue Background in Noninvasive Biochemical Detection | |
Ding H. Q.; Lu Q. P.; Gao H. Z. | |
2012 | |
发表期刊 | Spectroscopy and Spectral Analysis |
ISSN | 1000-0593 |
卷号 | 32期号:9页码:2347-2350 |
摘要 | In noninvasive biochemical detection, the differential spectrum method based on the change in blood volume can eliminate the interference of human tissue background in theory, and obtain effective spectrum information of blood. In order to demonstrate the effectiveness of the differential spectrum method, simulated experiment was designed. Biological molecules solutions were used for simulating serum sample, filters with different absorption characteristic were used for simulating interference of tissue background, and an adjustable path-length cell was used for simulating blood volume change. Model accuracies of pre- and post-treatment with differential spectrum method were compared. Thus treated, the root mean square error of cross validation (RMSECV) reduced from 437 to 301 mg . dL(-1). The experimental results indicate that using the differential spectrum method can effectively restrain the interference of tissue background, and greatly improve the prediction precision of calibration model. |
收录类别 | SCI |
语种 | 中文 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ciomp.ac.cn/handle/181722/34061 |
专题 | 中科院长春光机所知识产出 |
推荐引用方式 GB/T 7714 | Ding H. Q.,Lu Q. P.,Gao H. Z.. Experimental Study of Differential Spectrum Method for Elimination of Tissue Background in Noninvasive Biochemical Detection[J]. Spectroscopy and Spectral Analysis,2012,32(9):2347-2350. |
APA | Ding H. Q.,Lu Q. P.,&Gao H. Z..(2012).Experimental Study of Differential Spectrum Method for Elimination of Tissue Background in Noninvasive Biochemical Detection.Spectroscopy and Spectral Analysis,32(9),2347-2350. |
MLA | Ding H. Q.,et al."Experimental Study of Differential Spectrum Method for Elimination of Tissue Background in Noninvasive Biochemical Detection".Spectroscopy and Spectral Analysis 32.9(2012):2347-2350. |
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