Apoptotic effects of hypocrellin A on HeLa cells

	Apoptotic effects of hypocrellin A on HeLa cells
其他题名	论文其他题名
	Fei X. F.; Jie C.; Zheng K. Y.; Wei W.; Sun S. J.; Li W.; Lan M.; Cong L.; Teng L. R.
	2006
发表期刊	Chemical Research in Chinese Universities
ISSN	1005-9040
卷号	22 期号:6 页码:772-775
摘要	Hypocrellin A(HA), a photosensitive perylenequinone compound of Hypocrella bambusae, inhibited the proliferation of several tumor cell fines. Human cervical cancer cells, HeLa cells, were used as a model to elucidate the molecular mechanisms of HA-induced tumor cell death. The results show that HA can induce the oligonucleosomal fragmentation of DNA in HeLa cells and also can increase the expression of apoptosis inducer Bax mRNA and that it decreases the expression of apoptosis suppressor, Bel-2 mRNA, in mitochondria. It can be concluded from the data that HA-induced apoptosis is related to the balance between Bel-2 and Bax gene expressions.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/25746
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Fei X. F.,Jie C.,Zheng K. Y.,et al. Apoptotic effects of hypocrellin A on HeLa cells[J]. Chemical Research in Chinese Universities,2006,22(6):772-775.
APA	Fei X. F..,Jie C..,Zheng K. Y..,Wei W..,Sun S. J..,...&Teng L. R..(2006).Apoptotic effects of hypocrellin A on HeLa cells.Chemical Research in Chinese Universities,22(6),772-775.
MLA	Fei X. F.,et al."Apoptotic effects of hypocrellin A on HeLa cells".Chemical Research in Chinese Universities 22.6(2006):772-775.

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