Application of ring-opening metathesis polymerization in study of polymer molecular weight-mediated catalytic properties of immobilized lipase

	Application of ring-opening metathesis polymerization in study of polymer molecular weight-mediated catalytic properties of immobilized lipase
其他题名	论文其他题名
	Du C.; Zhang G.; Wang Z.; Li L.; Tang J.; Wang L.
	2009
发表期刊	Chinese Science Bulletin
ISSN	1001-6538
卷号	54 期号:3 页码:382-386
摘要	Recently, significant efforts have been devoted into the study of the effect of hydrophobic supports on the catalytic properties of immobilized lipases. It seems that immobilization lipases on hydrophobic supports is a simple and efficient method to improve the catalytic activity of lipases. In this study, the hydrophobic poly(N-propyl-norbornene-exo-2,3-dicarboximide)s with well-controlled molecular weight were synthesized by the living ring-opening metathesis polymerization, and the lipases from Pseudomonas sp. were then immobilized on these hydrophobic polymer supports through the physical adsorption. The immobilized lipases exhibited higher activity and enantioselectivity for the transesterification of 2-octanol than those of free lipases. Furthermore, we investigated the polymer molecular weight-mediated catalytic properties of immobilized lipases. It was found that the catalytic activity and E value of the immobilized lipases increased with the increase of the polymer molecular weight. At the polymeric molecular weight of about 40kDa, the highest E value (58 at 54.2% of conversion, enantiomeric excess = 99%) was reached. After the molecular weight of polymers getting higher than 40 kDa, catalytic activity and E value of the immobilized lipase decreased.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/25670
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Du C.,Zhang G.,Wang Z.,et al. Application of ring-opening metathesis polymerization in study of polymer molecular weight-mediated catalytic properties of immobilized lipase[J]. Chinese Science Bulletin,2009,54(3):382-386.
APA	Du C.,Zhang G.,Wang Z.,Li L.,Tang J.,&Wang L..(2009).Application of ring-opening metathesis polymerization in study of polymer molecular weight-mediated catalytic properties of immobilized lipase.Chinese Science Bulletin,54(3),382-386.
MLA	Du C.,et al."Application of ring-opening metathesis polymerization in study of polymer molecular weight-mediated catalytic properties of immobilized lipase".Chinese Science Bulletin 54.3(2009):382-386.

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