Study on Measurement of Cholesterol in Serum by Near-Infrared Spectroscopy and Applicability of Models

	Study on Measurement of Cholesterol in Serum by Near-Infrared Spectroscopy and Applicability of Models
其他题名	论文其他题名
	Yang H. M.; Lu Q. P.
	2011
发表期刊	Spectroscopy and Spectral Analysis
ISSN	1000-0593
卷号	31 期号:2 页码:375-378
摘要	To study rapid analysis of cholesterol concentration in human serum with no reagent, near-infrared spectroscopy was used. Applicability of analytical models was studied. Spectra of serum were measured by a FT-NIR spectrometer with 1, 2 and 6.5 mm optical path length respectively. Partial least-square (PLS) models were calibrated for cholesterol in combination, first overtone and second overtone spectral regions. Root mean square error of prediction (RMSEP) of these models is 0.15, 0.16 and 0.29 mmol.L(-1), and mean percent error of prediction (MPEP) is 2.9%, 3.1% and 4.8%, respectively. To validate applicability of these models, other two groups of serum spectra were measured in one month after the models were calibrated. These two sample groups were calculated using calibrated models. Prediction result of 1mm model is the best. The result of this experiment indicates that it's possible to calibrate precise models for cholesterol. If model is based on thinner samples, applicability is better.
收录类别	SCI
语种	中文
文献类型	期刊论文
条目标识符	http://ir.ciomp.ac.cn/handle/181722/25563
专题	中科院长春光机所知识产出
推荐引用方式 GB/T 7714	Yang H. M.,Lu Q. P.. Study on Measurement of Cholesterol in Serum by Near-Infrared Spectroscopy and Applicability of Models[J]. Spectroscopy and Spectral Analysis,2011,31(2):375-378.
APA	Yang H. M.,&Lu Q. P..(2011).Study on Measurement of Cholesterol in Serum by Near-Infrared Spectroscopy and Applicability of Models.Spectroscopy and Spectral Analysis,31(2),375-378.
MLA	Yang H. M.,et al."Study on Measurement of Cholesterol in Serum by Near-Infrared Spectroscopy and Applicability of Models".Spectroscopy and Spectral Analysis 31.2(2011):375-378.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
血清中胆固醇的近红外光谱测量及模型适用性（350KB）			开放获取	--	浏览下载